March 2017, VOLUME139 /ISSUE 3

Tsujii N, Shiraishi I, Kokame K, et al. Severe Hemolysis and Pulmonary Hypertension in a Neonate With Upshaw-Schulman Syndrome. Pediatrics. 2016:138(6):e20161565

Errors occurred in the article by Tsujii et al, titled “Severe Hemolysis and Pulmonary Hypertension in a Neonate With Upshaw-Schulman Syndrome” published in the December 2016 issue of Pediatrics (2016:138(6):e20161565;doi:10.1542/peds.2016-1565).

On page e1, under author contributions, the text reads “Dr Shraishi contributed to.” This should have read: “Dr Shiraishi contributed to.”

On page e3, in Fig 1, the text “D-dimer (μg/mL)” is printed in red. This should have printed in black. A replacement Fig 1 is provided here.


Clinical course and echocardiography findings. The upper panel shows TTE results. On days 1 and 3, the intraventricular septum (IVS) bows into the left ventricle (LV). This finding is not seen on days 5 and 7. IVIg, intravenous immunoglobin; RV, right ventricle.

On page e4, in Table 6, on line 6, the text reads: “3 × 109/L”. This should have read: “3 × 109/L”.

On page e5, the underline in Fig 2 is slight shifted. A replacement Fig 2 is provided here.


The c.415-10G>A mutation results in aberrant splicing. A, RT-PCR. The upper band (186 bp) was detected in patient RNA but not in normal subject RNA. B, the c.415-10G>A mutation resulted in a new splice acceptor site (underlined) and aberrant splicing, which caused the frame shift mutation.