Zhang et al, Nebulized Hypertonic Saline for Acute Bronchiolitis: A Systematic Review. Pediatrics. 2015;136(4):687–701; doi:10.1542/peds.2015-1914.
An error occurred in the article by Zhang et al, titled “Nebulized Hypertonic Saline for Acute Bronchiolitis: A Systematic Review” published in the October 2015 issue of Pediatrics (2015;136:687–701; doi:10.1542/peds.2015-1914).
On page 689, under Data Synthesis and Statistical Analysis, paragraph 3, on lines 14–15, “withdrawal rate >20%” should have read: “withdrawal rate >15% and intention-to-treat analysis not used.”
The authors also note that they erroneously included 1 unpublished inpatient trial (NCT01488448) that included patients with previous wheeze. Removal of this trial from the meta-analysis changes the results of hypertonic saline on length of stay from an MD of –0.45 days (95% confidence interval −0.82 to −0.08) to MD of –0.51 days (95% confidence interval −0.91 to −0.11). Exclusion of this trial from the subgroup analyses does not significantly affect the results.
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