16S bacterial rRNA analysis reveals influence of delivery mode on the neonatal microbiome. UniFrac analysis revealed similarities and clustering of bacterial communities based on the mother’s body habitat or the delivery mode of the newborn. Each colored point represents a similar community in specific body sites of the mother and all newborn body habitats.147 The percentage of variation of the principal coordinates analysis is indicated in white text on both axes. (Reproduced with permission from Dominguez-Bello MG, Costello EK, Contreras M, et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci USA. 2010;107[26]:11973.)