TABLE 1

Baseline Clinical Characteristics of Randomly Assigned Infants

Tight GroupControl Group
n4345
Gestational age, wk25 (24–27)25 (25–27)
Birth weight
 grams725 (660–870)825 (713–920)
 z score−0.31 ± 0.150.06 ± 0.18
Birth head circumference
 cm23.4 ± 0.224.1 ± 0.3
 z score−0.28 ± 0.190.29 ± 0.17
Birth length
 cm33.0 ± 0.533.5 ± 0.4
 z score−0.33 ± 0.16−0.17 ± 0.14
Male20 (47)22 (49)
SGA6 (14)7 (16)
Multiple birth16 (37)13 (29)
Antenatal steroid exposure37 (87)39 (86)
CRIB II score11 (10–14)12 (10–14)
Plasma cortisol at randomization, µg/dL10.8 (8.4–17.2)11.3 (8.4–16.9)
Ethnicity
 European12 (28)13 (29)
 Maori 15 (35)17 (38)
 Pacific Islander6 (14)8 (18)
 Asian10 (23)7 (15)
Age at randomization, d4 (2–7)5 (3–8)
  • Data are mean ± SEM, median (interquartile range), or number (%). CRIB, Clinical Risk Index for Babies.