TABLE 2

Total and Aeroallergen-Specific Serum IgE, eNO, and Serum Pneumoproteins in Children Who Swam as Infants and Their Controls

Swimming Infants (N = 43)Other Children (N = 298)P
Total IgE, median (interquartile range), kIU/La54.7 (24.6–162)55.8 (21.9–175).96
Aeroallergen-specific IgE
    Panel of 12 aeroallergens, n(%)b13 (30.2)95 (31.9).83
    House dust mite, n(%)b6 (14)57 (19.1).40
    Cat, n (%)b2 (4.7)17 (5.7).77
    Dog, n (%)b4 (9.3)8 (2.7).03
    Pollen, n (%)b7 (16.3)31 (10.4).26
eNO
    Median (interquartile range), ppba10.2 (7.15–14.1)8.9 (6.9–13.4).51
    >30 ppb, n(%)b3 (7.0)26 (8.7).70
Pneumoproteins
    CC16, mean (SD), μg/Lc,d8.0 (3.3)10.4 (4.2).01
    SP-D, mean (SD), μg/Lc113 (42)100 (45).08
    CC16/SP-D ratio, median (interquartile range)a,c0.07 (0.05–0.12)0.10 (0.07–0.16).003
  • a By 2-sided Mann-Whitney U test.

  • b By χ2 test.

  • c By 2-sided unpaired t test.

  • d Statistically significant after application of the Bonferroni's correction to the multiple comparisons of the lung epithelium markers (critical P = .05/3).