Crude and Adjusted OR With 95% CIs for Infantile Colic According to Maternal Use of NRT and Tobacco Smoking During the First and Second Trimester of Pregnancy

Nicotine ExposureInfantile Colic
Nn (%)Crude ORAdjusted OR1 (95% CI)Adjusted OR2 (95% CI)
Unexposed46 6603397 (7.3)1a1a1a
NRT users20723 (11.1)1.61.6 (1.0–2.5)1.6 (1.0–2.5)
Smokers15 01611 417 (9.4)1.31.3 (1.2–1.4)1.3 (1.2–1.4)
Smoking and NRT1245137 (11.0)1.61.5 (1.3–1.9)1.5 (1.3–1.8)
  • N, number; OR1, adjusted for maternal age, first parity, daily coffee consumption, weekly consumption, and binge-drinking episodes; OR2, further adjusted for couple’s combined educational and occupational status.

  • a Reference group.