Table 1.

Results of Clinical and Laboratory Evaluation at the Time of First Clinical Suspicion of Bacterial Infection and Initiation of Antibiotic Therapy and Between 24 and 48 Hours Later

Study
Group
No. (%) of Patients*Median of
CRP, mg/L
(range)
Clinical
Symptoms
ITQ
≥0.25
CRP
≥10 mg/L
At the time of clinical suspicion
 185  (90)82  (88)21  (22)4  (4–35)
 2a37  (95)32  (82)21  (54)12  (4–73)
 2b42  (98)38  (88)27  (63)16  (4–139)
 Total164  (93)152  (86)69  (39)5  (4–139)
Between 24 and 48 hours after initiation of antibiotic therapy
 117  (18)21  (22)0  (0)4  (4–9)
 2a20  (51)18  (46)39  (100)26  (10–82)
 2b14  (33)21  (49)43  (100)22  (10–138)
 Total51  (29)60  (35)82  (47)7  (4–138)
  • * ITQ indicates immature-total quotient; and CRP, C-reactive protein.