Table 4.

Minor Side Effects Reported Within 72 Hours of Immunization in 672 US Infants Receiving Tripedia DTaP or Connaught Whole-cell Pertussis Vaccine DTwP at 2, 4, and 6 Months of Age*

EventDose 1Dose 2Dose 3
DTaP, %
(n = 505)
DWwP, %
(n = 167)
DTaP, %
(n = 499)
DTwP, %
(n = 159)
DTaP, %
(n = 490)
DTwP, %
(n = 152)
Erythema (>1 inches)182827
Induration (>1 inches)113111111
Pain or tenderness1251744743
Drowsiness396018451626
Irritability357330722756
Anorexia627520619
Temperature >101°F and <104°F0.5428411
  • * Vaccines supplied by Connaught, Inc (Swiftwater, PA) and Connaught Ltd (Canada). Data are from package inserts.

  • DTaP compared with DTwP, all significant, P < .01. n indicates number of infants in each category.