TABLE 1

Signs and Symptoms of Osteogenesis Imperfecta

Fragile bones, with few, some, or many of the following findings:
    Poor linear growth
    Hypoplastic, translucent, carious, late-erupting, or discolored teeth
    Blue sclera
    Easy bruisability
    Limb deformities
    Scoliosis and/or kyphosis
    Hyperextensible joints
    Wormian bones
    Hearing impairment as a result of otosclerosis
    Inguinal and/or umbilical hernias
    Triangular-shaped face
    Macrocephaly
    Demineralized bones