APPENDIX

Prespecified Outcomes and Definitions Used for RCA

Influenza Vaccine TypeOutcomeICD-9 CM CodePrimary Postvaccination Follow-up Window (Secondary Window), d
AllGBS357.01–42
AllMyelitis, acute disseminated encephalomyelitis, and other encephalitis323.5, 323.51, 323.52, 323.6, 323.61, 323.62, 323.63, 323.8, 323.81, 323.82, 323.9, and 341.21–42 (1–21)
AllBell's palsy351.01–60 (1–42)
AllAnaphylaxis995.0 and 999.40–2
AllOther demyelinating disease (multiple sclerosis, demyelinating disease of central nervous system, optic neuritis, chronic inflammatory demyelinating polyneuropathy)340, 341.0, 341.8, 341.9, 377.30, 377.31, 377.32, 377.34, 377.39, and 357.811–42
AllDisorders of the peripheral nervous system and neuropathies (peripheral autonomic neuropathy, mononeuritis, peripheral neuropathy, polyneuropathy due to drugs or other toxic agents, critical illness polyneuropathy, other inflammatory and toxic neuropathy)337.0, 337.9, 354.1–354.9, 355.0–355.9, 356.4, 356.8, 357.6, 357.7, 357.82, 357.89, and 357.91–42
AllSeizures (epilepsy, convulsions)345.00–345.91, 780.3, 780.31, and 780.390–7 (0–14)
AllOther cranial nerve disorders350.1–350.9, 351.1, 351.8, 351.9, and 352.0–352.91–42
AllAtaxia334.31–42
AllAngioneurotic edema, allergic reaction, urticaria995.1, 995.3, 708.0, 708.1, and 708.91–2
AllSpontaneous abortion, missed abortion632 and 634.0–634.91–14
AllStillbornV27.1, V27.3, V27.4, V27.7, V32, V35, and V361–14
AllPreeclampsia, eclampsia642.4, 642.5, 642.6, and 642.71–14
AllHemorrhagic stroke430, 431, and 432.0–432.91–42
AllIschemic stroke433.01, 433.11, 433.21, 433.31, 433.81, 433.91, and 434.0–434.91–42
AllImmune thrombocytopenia287.31, 287.4, and 287.51–42 (7–28)
Live, attenuatedMyocarditis, pericarditis420.90, 420.91, 422.0, 422.90, 422.91, and 422.991–42
Live, attenuatedAsthma/wheezing493.0, 493.1, 493.9, 786.07, and 519.111–14
Live, attenuatedAsthma/wheezing /bronchiolitis466.1, 466.11, 466.19, 493.0–493.9, 786.07, 786.09, and 519.11–14 days (1–42)
  • ICD-9 indicates International Classification of Diseases, Ninth Revision.