Criteria for Diagnosis of FASD and Related Disorders

TerminologyDiagnostic Features
FASExplicit diagnostic criteria that include all of the following:
 Three facial abnormalities (ie, smooth philtrum, thin vermillion border, and small palpebral fissures). Also may see midface hypoplasia, micrognathia, microcephaly, epicanthal folds
 Growth deficiency (height and/or wt ≤10th percentile at any age)
 Structural, neurologic, or functional CNS abnormalities
 Prenatal exposure to alcohola
Partial FAS Some but not all of the physical features of full FAS (above)
 CNS damage (structural, neurologic, and/or functional impairment)
 Confirmed prenatal exposure to alcohol
Alcohol-related birth defects Classification for individuals who do not have the facial characteristics of full FAS
 Significant birth defects affecting the heart, eyes, kidneys, and/or bones resulting from PAE
 Hearing may also be affected
 Usually do not meet criteria for CNS structural or functional abnormalities
 Confirmed prenatal exposure to alcohol
Alcohol-related neurodevelopmental disorder Cluster of symptoms that may include intellectual disabilities as well as challenges with behavior and learning resulting from PAE
 May also have a CNS anomaly
 Often perform poorly in school and have difficulties with math, memory, attention, judgment, and impulse control
 Confirmed prenatal exposure to alcohol
ND-PAE Have impairment of neurocognition, self-regulation, and adaptive functioning
 Combines deficits in these 3 areas in conjunction with evidence of PAE, childhood onset of symptoms, and significant distress or impairment in social, academic, occupational, or other important area of function
 Confirmed prenatal exposure to alcohol