TABLE 2

Diagnostic Evaluations and Therapies of Children With CAP, Stratified According to Whether They Received Adjunct Systemic Corticosteroids

Overall (N = 20 703), n (%)No Systemic Corticosteroids (n = 13 469), n (%)Systemic Corticosteroids (n = 7234), n (%)P
Laboratory tests and procedures
    Chest computed tomography or ultrasound778 (3.8)694 (5.2)84 (1.2)<.001
    Respiratory virus tests3432 (20.9)2144 (20.4)1288 (21.7).051
    Arterial blood gas3399 (16.4)1972 (14.6)1427 (19.7)<.001
    Complete blood count12 540 (60.6)8548 (63.5)3992 (55.2)<.001
    Electrolytes7829 (37.8)5400 (40.1)2429 (33.6)<.001
    Urine culture2508 (12.1)2034 (15.1)474 (6.6)<.001
    Blood culture9580 (46.3)6709 (49.8)2871 (39.7)<.001
    C-reactive protein4561 (22.0)2871 (22.3)1690 (23.4).001
    Erythrocyte sedimentation rate1010 (4.9)854 (6.3)156 (2.2)<.001
    Early pleural drainage519 (2.5)480 (3.6)39 (0.5)<.001
    Mechanical ventilation823 (4.0)500 (3.7)323 (4.5).008
Therapies
    Chronic asthma medicationa3886 (18.8)1584 (11.8)2302 (31.8)<.001
    β-Agonist therapy10 971 (53.0)4788 (35.6)6183 (85.5)<.001
    Vasoactive infusions689 (3.3)313 (2.3)376 (5.2)<.001
Antibiotic regimen<.001
    Aminopenicillin1129 (5.5)593 (4.4)536 (7.4)
    Macrolide1780 (8.6)626 (4.7)1154 (16.0)
    Cephalosporin8751 (42.3)5914 (43.9)2837 (39.2)
    Macrolide and cephalosporin3160 (15.3)1829 (13.6)1331 (18.4)
    Cephalosporin and vancomycin/clindamycin2403 (11.6)1949 (14.5)454 (6.3)
    Macrolide and aminopenicillin217 (1.1)86 (0.6)131 (1.8)
    Macrolide, cephalosporin, and vancomycin/clindamycin304 (1.5)223 (1.7)81 (1.1)
    Other2959 (14.3)2249 (16.7)710 (9.8)
  • a Patients were considered to be on chronic asthma therapy if they received an inhaled steroid or a leukotriene-receptor antagonist on admission.