TABLE 4

Physicians' Antimicrobial of Choice for Treatment of GAS Pharyngitis in Children and Adolescents

AntimicrobialTotal No. (%) (n = 935)aNo. (%) of Pediatricians (n = 419)No. (%) of Family Physicians (n = 516)
First-line therapy (not penicillin-allergic)
    Penicillin-type antimicrobial889 (95)410 (98)479 (93)
        Amoxicillin586 (63)315 (75)271 (53)
        Oral penicillin281 (30)83 (20)198 (38)
        Benzathine penicillin, intramuscular21 (2)12 (3)9 (2)
        Ampicillin1 (<1)01 (<1)
    Extended spectrum penicillin-type antimicrobial13 (1)3 (<1)10 (2)
        Augmentin12 (1)3 (<1)9 (2)
        Dicloxacillin1 (<1)01 (<1)
    Macrolides14 (1)014 (3)
        Azithromycin12 (1)012 (2)
        Erythromycin, Clarithromycin2 (<1)02 (<1)
    Cephalosporins19 (2)6 (1)13 (3)
        First generation15 (2)4 (1)11 (2)
        Other4 (<1)2 (<1)2 (<1)
First-line therapy (penicillin-allergic):
    Macrolides680 (73)225 (54)455 (88)
        Azithromycin381 (41)145 (35)236 (46)
        Erythromycin266 (28)71 (17)195 (38)
        Clarithromycin33 (4)9 (2)24 (5)
    Cephalosporins241 (26)185 (44)56 (11)
        First generation177 (19)131 (31)46 (9)
        Other64 (7)54 (13)10 (2)
    Clindamycin11 (1)8 (2)3 (<1)
    Trimethoprim-sulfamethoxazoleb3 (<1)1 (<1)2 (<1)
  • Although physicians were instructed to indicate their top choice of antimicrobial, some physicians opted to list >1; in these cases, only the first antimicrobial listed was used in analyses.

  • a Note that there were missing responses, because not all 948 respondents chose to respond to the scenario.

  • b This is ineffective and inappropriate for GAS pharyngitis.