TABLE 4

CSF Parameters by Culture Results Showing Test Parameters and Positive (+) and Negative (−) Likelihood Ratios

VariableNegative (n = 8912)Positive (n = 95)aSensitivity, % (95% CI)Specificity, % (95% CI)LR+LR
WBC count, mm3
    05062
    1–82293897 (88–99)11 (10–12)1.090.92
    9–21891283 (71–91)61 (60–63)2.130.47
    22–100591879 (67–89)81 (80–82)4.160.24
    >1002853866 (52–78)94 (93–95)110.09
    Unknown434637
Glucose, mg/dL
    <20252444 (30–58)98 (97–99)220.05
    20–6035042589 (78–96)20 (18–21)1.110.90
    >608606
    Unknown452340
Protein, mg/dL
    0–40830
    41–9016169100.00 (84–100)2 (1–3)1.020.98
    90–1201073484 (71–92)28 (27–29)1.170.86
    >12016244276 (63–87)63 (62–64)2.050.49
    Unknown451640
  • LR indicates likelihood ratio; CI, confidence interval.

  • a Coagulase-negative staphylococci and known skin flora are excluded here.