TABLE 10

Therapeutic Options for Chronic Diarrhea in Children

TherapyUnderlying Cause
Symptomatic therapy with antisecretory medicationSevere diarrheal disease as an empiric trial before end of diagnostic workup
Severe idiopathic diarrhea
Drug therapyChronic intestinal infections and small-bowel bacterial overgrowth
Malabsorption
Inflammatory bowel diseases and autoimmune enteropathy
Short-bowel syndrome and other chronic secretory diarrheal disorders
SurgeryMalrotation
Stenosis
Blind loops
Intestinal transplantationShort-bowel syndrome
Intestinal pseudo-obstruction and other disorders of defective intestinal motility
Ultrastructural enterocyte abnormalities
  • Data source: Canani RB, Cirillo P, Terrin G. Chronic and intractable diarrhea. In: Guandalini S, ed. Essential Pediatric Gastroenterology, Hepatology, and Nutrition. New York, NY: McGraw-Hill Medical Publishing Division; 2005:41– 42.