TABLE 1

Time to 25% Cumulative Probability of HONC Symptoms and Smoking Frequency Among Subjects Who Had Initiated Smoking

HONC SymptomsProportion Reporting Symptom (N = 370), %aTime to 25% Cumulative Probability, Estimate (95% CI), mob
Diminished autonomy (any symptom)32.727.0 (21.0–37.0)
Strong desire to smoke
    Have you ever had strong cravings to smoke?27.037.1 (30.6–55.5)
    Have you ever felt like you really needed a cigarette?27.339.0 (28.2–53.8)
Withdrawal symptoms
    When you have tried to stop smoking or when you haven't been able to smoke …
    Did you feel a strong need or urge to smoke?21.155.5 (35.0–83.9)
    Did you feel more irritable because you couldn't smoke?18.176.9 (40.8–90.1)
    Did you feel nervous, restless, or anxious because you couldn't smoke?16.873.7 (40.5–??)
    Did you find it hard to concentrate because you couldn't smoke?15.486.4 (55.0–131.4)
Feeling addicted
    Have you ever felt like you were addicted to tobacco?19.763.6 (42.3–80.0)
Difficulty controlling use
    Have you ever tried to quit smoking but couldn't?14.383.2 (56.2–123.8)
    Do you smoke now because it is really hard to quit?13.590.1 (56.0–??)
    Is it hard to keep from smoking in places where you are not supposed to, like school?10.0?? (74.1–??)
Symptom groups
    Strong desire to smoke30.830.6 (24.5–42.3)
    Withdrawal symptoms25.143.6 (30.0–63.0)
    Feeling addicted19.763.6 (42.3–80.0)
    Difficulty controlling use18.957.2 (43.1–79.9)
Smoking frequency
    Monthly37.023.8 (13.0–30.9)
    Daily24.650.5 (32.7–64.1)
  • a Proportion of the cohort reporting each symptom. Each student could report >1 symptom.

  • b For some outcomes, there were not enough events to estimate the 25% cumulative probability.