TABLE 3.

Overall Pneumococcal Serotypes and Antibiotic Resistance by Surveillance Period*

SerotypesYearPCN-I, % (n)PCN-R, % (n)PNSP, % (n)E-NS, % (n)Clin-NS, % (n)T/S-NS, % (n)Ctx-NS, % (n)MDR1, % (n)MDR2, % (n)
PCV7200112% (6)33% (17)45% (23)35% (18)12% (6)41% (21)27% (14)43% (22)31% (16)
200419% (6)38% (12)56% (18)34% (11)13% (4)47% (15)6% (2)44% (14)38% (12)
P = .02
PCV7–cross-reactive200128% (12)23% (10)51% (22)19% (8)0% (0)51% (22)16% (7)40% (17)9% (4)
200443% (30)10% (7)54% (37)32% (22)4% (3)26% (18)4% (3)35% (24)20% (14)
P = .06P = .009P = .04
Non-PCV720012% (1)6% (3)8% (4)6% (3)0% (0)8% (4)6% (3)2% (1)2% (1)
200416% (20)9% (11)25% (31)14% (18)11% (14)14% (18)0% (0)14% (18)10% (13)
P = .009P = .01P = .01P = .02P = .02
Total200113% (19)21% (30)34% (49)20% (29)4% (6)33% (47)17% (24)28% (40)15% (21)
200425% (56)13% (30)38% (86)23% (51)9% (21)23% (51)2% (5)25% (56)17% (39)
P = .008P = .06P = .04P < .0001
  • PCN indicates penicillin; E, erythromycin; Clin, clindamycin; T/S, trimethoprim-sulfamethoxazole; Ctx, ceftriaxone; I, intermediate-level resistance; R, high-level resistance; NS, nonsusceptible.

  • * Two-tailed Fisher exact tests are provided comparing changes in proportional antimicrobial susceptibility within vaccine groups between 2001 and 2004 isolates.

  • Based on isolates with both antibiotic susceptibility and serotype data. In 2001, 23 isolates were lost after antibiotic susceptibility tests but before serotyping.