TABLE 2

Performance of RIDT Compared With rRT-PCR for the Diagnosis of 2009 H1N1 Influenza A Virus Infection in Pediatric Patients for 3030 Specimens

CharacteristicnSensitivity, % (95% CI)Specificity, % (95% CI)Positive LR (95% CI)Negative LR (95% CI)
Overall303045.0 (43.3–46.3)98.6 (98.1–99.0)32.9 (23.4–46.7)0.56 (0.54–0.58)
Upper airwaya288044.6 (43.0–45.7)98.9 (98.4–99.2)39.3 (26.7–58.4)0.56 (0.55–0.58)
    Nasal wash183643.5 (41.1–45.4)98.6 (97.9–99.0)30.4 (19.9–46.9)0.57 (0.55–0.60)
    Nasal swab101645.5 (43.6–46.3)99.4 (98.6–99.8)81.5 (32.2–211.3)0.55 (0.54–0.57)
    Sputum17100.0 (55.8–100.0)100.0 (90.5–100.0)0.00 (0.00–0.49)
Lower airway14058.3 (35.0–77.2)95.3 (93.1–97.1)12.4 (5.1–26.5)0.44 (0.24–0.70)
    Tracheal aspirate12754.5 (30.9–74.1)95.7 (93.4–97.5)12.7 (4.7–30.1)0.48 (0.27–0.74)
    Bronchoalveolar lavage13100.0 (23.0–100.0)91.7 (85.2–91.7)12.0 (1.5–12.0)0.00 (0.00–0.91)
  • a Nasopharynx (n = 11) was not reported in this subcategory, because there were no positive results with the RIDT.