TABLE 38.

Neonatal Hyperbilirubinemia Screening

SourceLocation and Type of TrialInterventionNeonatal Hyperbilirubinemia Detection
Bilgen et al632Turkey; urban hospital setting; QTTranscutaneous measurements were obtained from newborns (n = 96) with a Minolta AirShield bilirubinometer and an Ingram icterometer and compared to serum bilirubin measures.A linear correlation existed between serum bilirubin values and the readings on both the Minolta bilirubinometer (r = 0.83) and the Ingram icterometer (r = 0.78).
Riskin et al633Israel; urban urban hospital setting; PCS4 neonatologists were asked to estimate visually the level of bilirubin in a group of term clinically jaundiced infants (n = 283) before discharge from the nursery on the third day of life. Their clinical estimation was compared with actual measurement of serum total bilirubin from samples drawn simultaneously.Clinical visual estimation of serum total bilirubin had a high correlation to actual serum bilirubin levels as measured by spectrophotometer (r = 0.682; P < .001).
Kumar et al627India; urban hospital setting; RCTTerm babies (n = 100) were randomly selected for estimation of transcutaneous bilirubin (by Minolta AirShield bilirubinometer 101) and serum bilirubin levels by conventional diazo method. Babies needing phototherapy (n = 40) were randomized into 2 groups: (1) those having their transcutaneous bilirubin level measured from a covered area on the forehead, and (2) those who did not have a covered area on the forehead.There was a linear correlation (r = 0.9090; P < .001) between serum bilirubin level and transcutaneous bilirubin level. In the babies requiring phototherapy, there was significant (P < .001) linear correlation between prephototherapy and postphototherapy readings, group 1 (r = 0.69) and group 2 (r = 0.80).
Bhutta et al629Pakistan; urban hospital setting; QTTranscutaneous bilirubinometry was compared with standard laboratory estimation of bilirubin level in normal jaundiced newborns (n = 65).Transcutaneous bilirubinometry was not very effective in recognizing hyperbilirubinemia in comparison with biochemical testing, especially among dark infants. Although the correlation between the 2 methods was significant (r = 0.66; P < .01), the scatter was wide and the specificity was only 53%.
Narayanan et al630India; urban hospital setting; QTEffectiveness of the icterometer was evaluated in detecting neonatal hyperbilirubinemia in newborn infants (n = 158).There was positive correlation between the readings on the nose and serum bilirubin levels (P < .05).