TABLE 1.

Characteristics of Patients With HUS

CharacteristicAll PatientsWith OligoanuriaWithout OligoanuriaP
Sample size, n (%)29 (100)16 (55.2)13 (44.8)
Female gender, n (%)13 (44.8)9 (56.3)4 (30.8).264
Age, y
    Median3.13.53.1.125
    Range0.8–8.81.9–8.80.8–7.1
Race or ethnic group, n (%)
    White24 (82.8)14 (87.5)10 (76.9).780
    Hispanic4 (13.8)2 (12.5)2 (15.4)
    Black0 (0)0 (0)0 (0)
    Asian or Pacific Islander1 (3.4)0 (0)1 (7.7)
    Native American0 (0)0 (0)0 (0)
Bloody diarrhea, n (%)*26 (89.7)14 (87.5)12 (92.3)1.0
Vomiting, n (%)23 (79.3)14 (87.5)9 (69.2).364
Antibiotics before HUS, n (%)10 (34.5)8 (50.0)2 (15.4).114
Antimotility agents before HUS, n (%)5 (17.2)4 (25.0)1 (7.7).343
Category of enrollment, n (%)
    Culture19 (65.5)9 (56.3)10 (76.9)
    Contact1 (3.4)0 (0.0)1 (7.7)
    Bloody diarrhea2 (6.9)1 (6.3)1 (7.7).151
    HUS7 (24.1)6 (37.5)1 (7.7)
Initial laboratory tests
    White cell count, × 103/mm3
        Median14.218.611.2.018
        Range8.5–29.98.5–29.98.5–21.7
    Initial platelet count, × 103/mL
        Median280206338.037
        Range44–53044–53049–409
    Initial hematocrit, %
        Median35.132.937.6.148
        Range16–4821–4616–48
    Initial serum creatinine, mg/dL
        Median0.40.60.4.007
        Range0.1–5.50.3–5.50.1–1.7
    Initial serum urea nitrogen concentration, mg/dL
        Median12138.087
        Range2–863–862–86
Characteristics of HUS
    Serum sodium concentration on first day of HUS, mEq/L
        Median134132137.001
        Range125–140125–138132–140
    Days of oligoanuria
        Median88
        Range1–321–32
    Dialysis16 (55.2)16 (100)0 (0)<.001
    Days of dialysis
        Median88
        Range3–313–31
    Length of hospital stay, d
        Median9126<.001
        Range1–567–561–9
Intravenous fluids received before onset of HUS
    Children receiving intravenous fluids at any time before diagnosis of HUS being made, n (%)25 (89.7)13 (81.3)12 (92.3).606
    Volume of intravenous fluids administered at any time before diagnosis of HUS being made, L/m2
        Median6.445.248.92.019
        Range0–20.530–8.912.44–20.53
    Sodium administered via intravenous fluids at any time before diagnosis of HUS being made, mEq/m2
        Median8754821185.004
        Range0–27540–13720–2754
    Free water administered as intravenous fluids at any time before diagnosis of HUS being made, L/m2
        Median0.350.600.05.495
        Range0–13.220–4.170–13.22
    Children who received intravenous fluids in the first 4 d of illness, n (%)20 (69.0)8 (50.0)12 (92.3).020
  • Day 1 of illness was defined as the first day of diarrhea. — indicates that the variable is not applicable.

  • * Blood was not observed in the stool in 2 children in the oligoanuric group and in 1 child in the nonoligoanuric group.

  • Number of days that patients were hospitalized after the diagnosis of HUS.