TABLE 2

Most Common Underlying Conditions in Children With Invasive Pneumococcal Infections: 1994–2000 Versus 2001–2008

Underlying Condition1994–2000, n (%)2001–2008, n (%)
Malignancies144 (16)127 (23)
Central nervous system143 (16)63 (11)
Cardiovascular115 (13)49 (9)
HIV80 (9)18 (3)
Hemoglobinopathy72 (8)26 (5)
Renal71 (8)36 (7)
Other268233
Total893552