Most Common Underlying Conditions in Children With Invasive Pneumococcal Infections: 1994–2000 Versus 2001–2008
| Underlying Condition | 1994–2000, n (%) | 2001–2008, n (%) |
|---|---|---|
| Malignancies | 144 (16) | 127 (23) |
| Central nervous system | 143 (16) | 63 (11) |
| Cardiovascular | 115 (13) | 49 (9) |
| HIV | 80 (9) | 18 (3) |
| Hemoglobinopathy | 72 (8) | 26 (5) |
| Renal | 71 (8) | 36 (7) |
| Other | 268 | 233 |
| Total | 893 | 552 |