TABLE 2.

Adverse Events Among Randomized Participants (N = 120), Listed In Order of Decreasing Overall Frequency, According to Treatment Group

Patch (476 person-wk)Gum (552.1 person-wk)Placebo (439.9 person-wk)Elevated in Active-Medication Group, Compared with Placebo
Pruritus446125Patch, P = .033; gum, P = .003
Erythema493923Patch, P = .0045
Headache242636
Fatigue152032
Viral infection143019
Insomnia131713
Cough9158
Nausea101011
Jaw pain10128
Anxiety6137
Sore throat3183Gum, P = .0007
Hiccups4144Gum, P = .014
Dyspepsia4108
Shoulder or arm pain1503Patch, P = .00011
Dizziness339
Congestion334
Edema424
Constipation300
Diarrhea002