TABLE 1

What the USPSTF Grades Mean and Suggestions for Practice

GradeGrade DefinitionsSuggestions for Practice
AThe USPSTF recommends the service. There is high certainty that the net benefit is substantial.Offer/provide this service.
BThe USPSTF recommends the service. There is high certainty that the net benefit is moderate or there is moderate certainty that the net benefit is moderate to substantial.Offer/provide this service.
CThe USPSTF recommends against routinely providing the service. There may be considerations that support providing the service in an individual patient. There is moderate or high certainty that the net benefit is small.Offer/provide this service only if there are other considerations in support of the offering/providing the service to an individual patient.
DThe USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits.Discourage the use of this service.
I statementThe USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of the service. Evidence is lacking, of poor quality, or conflicting, and the balance of benefits and harms cannot be determined.Read “Clinical Considerations” in the USPSTF recommendation statement. If offered, patients should understand the uncertainty about the balance of benefits and harms.