TABLE 3

Six-Month Frequency and Proportion of Ever Experiencing Episode of Influenza-like Symptoms and Antibiotic Use During Intervention, According to Study Group

Symptom/Prescriptionn (%)P
Placebo (N = 104)Lactobacillus acidophilus (N = 110)L acidophilus/Bifidobacterium lactis (N = 112)Placebo vs L acidophilusPlacebo vs L acidophilus/B lactisL acidophilus vs L acidophilus/B lactis
Fever66 (63.5)31 (28.2)18 (16.1).0085.0009.32
Cough87 (83.7)51 (46.4)33 (29.5).027.005.44
Rhinorrhea85 (81.7)61 (55.5)35 (31.3).68.03.088
Antibiotics57 (54.8)18 (16.4)9 (8.0).0002<.0001.286
  • An episode was defined as a continuous display of symptoms measured in days (24 hours from the start of a school day). Symptom-free was defined as a continuous period free of symptoms measured in days (24 hours from the start of a school day). Symptoms displayed by a child for part of a day were considered to be experienced for the whole day.