TABLE 3

Postnatal Factors Associated With Pulmonary Deterioration

Postnatal FactorLow Fio2 (N = 249), Column %Pulmonary Deterioration (N = 484), Column %EPPD (N = 576), Column %Row NP
SNAP-II
    <20705440658≤.0005
    20–29182727326
    ≥30111933305
Surfactant in the first week7889971180≤.0005
Bacteremia
    Confirmed131618213≤.0005
    Presumed sepsis273441465
    No605141631
Medications during the first 2 wk
    Methylxanthines988052927≤.0005
    Hydrocortisone21116151≤.0005
    Dexamethasone21431.03
    Analgesics456174836≤.0005
    Sedatives121930294≤.0005
    Vitamin A202536382≤.0005
PDA diagnosis
    Clinical121614190≤.0005
    Echo364857654
    None523628465
PDA treatment
    None655345679≤.0005
    Indomethacin314146540
    Ligation46990
Highest level of ventilatory support on day 0
    No support0001≤.0005
    Hood0
    Cannula0.40.202
    CPAP196184
    Conventional MV7180771008
    High frequency101422214
Highest level of ventilatory support on day 7
    No support183062≤.0005
    Hood00.201
    Cannula1197110
    CPAP503010325
    Conventional MV195259641
    High frequency2525169
CLD175167620≤.0005
  • MV indicates mechanical ventilation; CPAP, continuous positive airway pressure.