TABLE 5.

Comparative AOM Outcomes for Initial Observation Versus Antibacterial Agent*

AOM OutcomeInitial Antibacterial TherapyInitial ObservationP Value
Symptomatic relief at 24 hours37,7260%59%NS
Symptomatic relief at 2–3 days7291%87%NS
Symptomatic relief at 4–7 days7279%71%NS
Clinical resolution at 7–14 days7282%72%NS
Pain duration, mean days732.83.3NS
Crying duration, mean days730.51.4<.001
Analgesic use, mean doses662.34.1.004
Fever duration, median days662.03.0.004
Incidence of mastoiditis or suppurative complications10.59%0.17%NS
Persistent MEE at 4–6 weeks7245%48%NS
Persistent MEE at 3 months7221%26%NS
Antibacterial-agent-induced diarrhea or vomiting7416%
Antibacterial-agent-induced skin rash742%
  • * NS indicates not significant.