TABLE 3

Regression Estimates of Child 3-Year Adiposity-Related Measures on Continuous Cord Blood Leptin (per 10 ng/mL) and Adiponectin (per 10 μg/mL) Exposures

VariableCord Blood LeptinCord Blood Adiponectin
Estimate (95% CI)PEstimate (95% CI)P
BMI z score at 3 y of age
    M1−0.09 (−0.22 to 0.04).200.06 (−0.07 to 0.18).38
    M2−0.16 (−0.30 to −0.02).020.08 (−0.04 to 0.21).18
    M3−0.29 (−0.43 to −0.14).00010.07 (−0.06 to 0.19).29
Weight-for-age z score at 3 y of age
    M1−0.03 (−0.15 to 0.10).670.001 (−0.12 to 0.12).98
    M2−0.10 (−0.23 to 0.03).150.03 (−0.09 to 0.15).63
    M3−0.28 (−0.42 to −0.14)<.00010.002 (−0.11 to 0.12).98
Height-for-age z score at 3 y of age
    M10.05 (−0.07 to 0.17).42−0.08 (−0.19 to 0.03).16
    M2−0.00 (−0.14 to 0.14).99−0.07 (−0.19 to 0.05).26
    M3−0.16 (−0.30 to −0.02).03−0.10 (−0.21 to 0.02).10
Leg length at 3 y of age
    M1−0.20 (−0.59 to 0.19).30−0.42 (−0.79 to −0.05).02
    M2−0.06 (−0.41 to 0.30).75−0.09 (−0.40 to 0.22).57
    M3−0.40 (−0.77 to −0.04).03−0.16 (−0.46 to 0.15).31
SS + TR
    M10.19 (−0.36 to 0.74).500.40 (−0.11 to 0.91).13
    M2−0.02 (−0.63 to 0.58).940.45 (−0.08 to 0.98).09
    M3−0.24 (−0.88 to 0.41).480.42 (−0.11 to 0.95).12
SS/TR
    M10.92 (−1.03 to 2.87).351.83 (0.01 to 3.66).05
    M2−0.43 (−2.64 to 1.79).711.96 (0.04 to 3.88).05
    M3−0.22 (−2.61 to 2.17).862.01 (0.09 to 3.93).04
3-y leptin
    M10.59 (0.27 to 0.91).00030.20 (−0.06 to 0.47).14
    M20.59 (0.28 to 0.90).00020.23 (0.00 to 0.45).05
    M30.58 (0.25 to 0.92).0010.20 (−0.03 to 0.43).08
3-y adiponectin
    M1−1.15 (−2.26 to −0.03).040.65 (−0.26 to 1.56).16
    M2−0.91 (−2.22 to 0.41).180.61 (−0.36 to 1.57).22
    M3−1.38 (−2.81 to 0.05).060.55 (−0.42 to 1.52).27
  • M1 was unadjusted. M2 was adjusted for maternal education, prepregnancy BMI, gestational weight gain and duration of gestation; paternal BMI; and child age, gender, race/ethnicity, and breastfeeding duration. SS/TR outcome was additionally adjusted for BMI z score at 3 years of age. M3 was M2 plus BW/GA z score.