TABLE 4.

Mean Serum and Creatinine-Corrected 12-Hour Urinary-Free Cortisol Concentrations in Children Aged 12–47 Months With Persistent/Recurrent Wheeze After Treatment With FP or SCG for 52 Weeks

FPSCG
Serum cortisol (nmol/L), all samples
 Week 0240.7 (56.9)216.9 (73.0)
n = 410n = 134
 Week 52 geometric mean ratio0.971.09
n = 289n = 94
 FP/SCG ratio0.90; 95% CI: 0.81–1.00; P = .050
12-h urinary cortisol adjusted for creatinine (nmol/mmol)
 Week 030.3 (73.7)28.7 (58.7)
n = 430n = 140
 Week 28 geometric mean ratio0.891.15
n = 358n = 118
 FP/SCG ratio0.82; 95% CI: 0.73–0.92; P < .001
 Week 52 geometric mean ratio0.911.12
n = 342n = 110
 FP/SCG ratio0.86; 95% CI: 0.76–0.96; P = .008
  • Results are expressed as geometric mean (coefficient of variation).