Difference Between Definite and Possible Diagnosis of IE Using the Modified Duke Criteria

Definite IE (n = 36) (%)Possible IE (n = 5) (%)P Value
Major criteria
 Positive BC/serology52.80.027*
 Positive echocardiographic examination97.280NS
 New valvular regurgitation52.820NS
Minor criteria
 Vascular phenomena22.20NS
 Immunologic phenomena2.70NS
 Microbiologic evidence other than major criteria13.920NS
  • NS indicates not significant.

  • * Specificity: 100%; sensitivity: 79.2%; positive predictive value: 100%.

  • Specificity: 20%; sensitivity: 97.2%; positive predictive value: 89.7%.