TABLE 1.

Sensitivity, Specificity, and Predictive Values of Markers of SBI

Sensitivity (% [95% CI])Specificity (% [95% CI])NPV (%)PPV (%)
PCT (*0.5 ng/mL)93 (77–99)74 (62–84)9660
CRP (*40 mg/L)79 (60–92)79 (67–88)9061
Leukocytes ≥15 G/L52 (33–71)74 (62–84)7845
Band ≥1.5 G/L11 (2–28)93 (84–98)7238
Leukocytes ≥15 G/L or band ≥1.5 G/L55 (36–74)72 (61–83)8046
IL-6 (*100 pg/L)36 (13–65)80 (64–91)7738
YOS score >1023 (5–54)82 (67–92)7630
  • NPV indicates negative predictive value; PPV, positive predictive value; YOS, Yale observation scale; CI, confidence interval.

  • * Cutoff.