TABLE 3.

Observed Risk of Anaphylaxis After Specific Vaccines*

VaccineNo. of Doses AdministeredNo. of Cases of AnaphylaxisRisk per Million Doses (95% CI)
DT47 171121.2 (0.5–118.1)
DTP788 80711.3 (0.03–7.1)
DTaP448 45600 (0–8.2)
DTP-Hib596 64523.4 (0.4–12.1)
Influenza197 96400 (0–18.6)
Hepatitis A23 18500 (0–159.1)
Hepatitis B1 852 14721.1 (0.1–3.9)
Hib785 01011.3 (0.03–7.1)
IPV48 06200 (0–76.7)
MMR848 94533.5 (0.7–10.3)
OPV1 546 37231.9 (0.4–5.7)
Td152 63600 (0–24.2)
Varicella254 18600 (0–14.5)
Other54 46300 (0–67.7)
TOTAL7 644 04950.65 (0.21–1.53)
  • DTaP indicates diphtheria-tetanus-acellular pertussis; IPV, inactivated polio vaccine; Td, adult diphtheria-tetanus.

  • * Includes vaccines administered in combination with other vaccines.

  • If risk is 0, the CI is 1-sided 97.5% CI.