TABLE 3

BMD Annual Growth (g/cm2 per year) by Gender, Tanner Stage, and BMI-for-Age Percentiles

ParameterBMI-for-Age PercentilesTotalPb
Quartile 1Quartile 2Quartile 3Quartile 4
RateaNo. of VisitsRateaNo. of VisitsRateaNo. of VisitsRateaNo. of VisitsRateaNo. of Visits
Boys
    Tanner stage
        10.0202520.0202210.0251880.0302140.023875<.0001
        20.0201710.0261410.0281160.0301430.027571.0700
        30.032700.045670.048780.053790.045294.0010
        40.061860.074920.0771000.074880.071366.1500
        50.0611340.0651700.0741860.0641770.065667.0700
        Total0.0307130.0386910.0456680.0467010.0402773<.0001
Girls
    Tanner stage
        10.0241470.0241000.021760.027710.023394.0300
        20.056790.057720.058880.058790.057318.9900
        30.076750.084800.084720.088750.082302.2000
        40.050610.071900.081880.104570.071296<.0001
        50.017510.029980.0341350.0381480.032432.0700
        Total0.0394130.0514400.0454590.0544300.0461742<.0001
  • a Rate (median) = (BMD at current visit − BMD at previous visit)/years since last visit; Tanner stage (determined by genital stage for boys and breast stage for girls) and BMI-for-age percentile determined at current visit.

  • b Obtained from simple linear regression of the ranks of BMD rate on quartile of BMI-for-age percentile accounting for correlation of repeated measurements on same individual; P value for the test of the interaction of Tanner stage and quartile of BMI-for-age percentile on BMD annual growth was .07 for boys and .04 for girls.