TABLE 3

Comparison of Adult and Child Studies According to Study Design

Study DesignAdult Studies, n (% of Adult Studies)Child Studies, n (% of Child Studies)P
All study designs189 (100)181 (100)
RCT45 (23.8)16 (8.8)<.001
Systematic review and meta-analysis20 (10.6)3 (1.7)<.001
Cohort study (retrospective or prospective)65 (34.4)54 (29.8).35
Case-control study6 (3.2)5 (2.8).82
Cross-sectional study32 (16.9)74 (40.9)<.001
Clinical trial (nonrandomized)3 (1.6)6 (3.3).33
Case series5 (2.7)7 (3.9).5
Case report5 (2.7)11 (6.1).1
Diagnostic test study2 (1.1)3 (1.7).62
Other6 (3.2)2 (1.1).28