TABLE 1

Baseline Characteristics in Both Recruitment Groups

CharacteristicConventional (n = 2110)Alternative (n = 448)Total (N = 2558)
Age of introduction cow milk products, n (%)
    0–3 mo946 (45)49 (11)995 (39)
    4–6 mo687 (33)138 (31)825 (32)
    7–9 mo434 (21)234 (52)668 (26)
    >9 mo43 (2%)27 (6)70 (3)
Age of introduction other foods products, n (%)
    3 mo183 (9)22 (5)205 (8)
    4–6 mo1880 (90)397 (89)2277 (89)
    >7 mo47 (2)29 (7)76 (3)
Use of hypoallergenic formulas, n (%)
    Yes150 (7)22 (5)172 (7)
Breastfeeding, n (%)
    Never377 (18)11 (3)388 (15)
    0–3 mo797 (38)56 (13)853 (33)
    4–6 mo357 (17)70 (16)427 (17)
    7–9 mo280 (13)111 (25)391 (15)
    >9 mo250 (12)196 (44)446 (17)
    Unknown49 (2%)4 (1)53 (2)
Gender of infants (boys) n (%)1083 (51)230 (51)1313 (51)
Maternal age, mean (SD), y32 (4)34 (4)32 (4)
Maternal smoking during pregnancy, n (%)174 (8)2 (<1)176 (7)
Environmental tobacco smoke exposure, n (%)107 (5)2 (<1)109 (4)
Maternal education, n (%)
    Low239 (11)17 (4)256 (10)
    Middle814 (39)79 (18)79 (35)
    High943 (45)341 (76)341 (50)
    Unknown114 (5)11 (3)125 (5)
Parental allergic disease, n (%)
    Both parents nonallergic842 (40)173 (39)1015 (40)
    Only father allergic450 (21)102 (23)552 (22)
    Only mother allergic468 (22)102 (23)570 (22)
    Both parents allergic284 (14)65 (15)349 (14)
    Unknown66 (3)6 (1)72 (3)
Sibling history of atopic manifestations, n (%)
    No siblings1734 (82)343 (77)2077 (81)
    ≥1 sibling(s), all nonatopic235 (11)69 (15)304 (12)
    ≥1 sibling(s), at least 1 atopic83 (4)33 (7)116 (5)
    Unknown58 (3)3 (1)61 (2)
Infants atopic outcome at 2 y of age, n (%)
    Eczema665 (31)128 (29)783 (31)
    AD UK-WP (n = 822)a85 (14)24 (11)109 (13)
    Recurrent wheeze230 (11)29 (7)259 (10)
    Sensitization (overall) (n = 782)a164 (30)56 (25)220 (28)
    Sensitization against cow milk (n = 789)a115 (20)35 (16)150 (19)
    Sensitization against (hen) egg (n = 789)a38 (7)9 (4)47 (6)
    Sensitization against peanut (n = 789)a36 (6)6 (3)42 (5)
    Sensitization against at least 1 inhalant allergen (n = 756)a55 (10)29 (13)84 (11)
  • Numbers may not add up total because of missing values.

  • a Available only for infants who had a home visit.