TABLE 2

Diagnostic Testing for POI, KPNW, August 2006 to December 2014

TestN (%)
ACOG tests
 FSH tested43 (94)
 FSH tested on at least 2 separate occasions33 (72)
 FSH was abnormala on at least 2 separate occasions33 (72)
 Estradiol tested36 (78)
 Estradiol tested on at least 2 separate occasions16 (35)
 Estradiol was abnormala on at least 2 separate occasions9 (20)
 Met ACOG POI case definitionb9 (20)
Other diagnostic tests
 Abnormal antimullerian hormone4 (9)
 Antiadrenal antibodies0 (0)
 Thyroperoxidase antibodies4 (9)
  • a Abnormal is defined as being in the postmenopausal range by using reference values documented in the medical record. Reference values varied by patient age, reference laboratory, and the timing of collection relative to menstrual cycle and hormonal therapy use.

  • b ACOG POI case definition requires the presence of menstrual irregularity for at least 3 mo, elevated FSH in the postmenopausal range, and low estradiol levels on 2 separate occasions.