TABLE 4.

Treatment, Follow-Up, and Outcomes of Study Infants

CaseAcute SymptomsFollow-Up and CommentsNeurologic ExaminationPEDS, AgeCBC-LMPC ScoreIQ at Age 5VMI (Standard Score)
1NoneDeclined full participation in JIFee (“No time”) but completed questionnairesNormal by primary pediatrician at 4.5 yearsNo concerns, age 5NormalNot doneNot doneNot done
2NoneCompleted JIFee evaluation. Comment by psychologist: “Excelled in tasks of manipulating visual information, such as copying geometric figures, and also excelled in arithmetic. Motorically quite active.”Normal by child neurologistNo concerns, age 5Normal5Performance IQ = 129; Verbal IQ = 105Visual = 113; Motor = 130
3NoneDied of apparent SIDS; see text. No kernicterus at autopsy.Not doneNot doneNot doneNot doneNot doneNot done
4NoneCompleted JIFee evaluation. Comment by psychologist: “Bright. Better nonverbal than verbal. Articulation problems but overall could be understood and talkative.”Normal/questionable by child neurologist-hyperreflexia and “mildly ataxic at saying “lala’”No concerns, age 5Normal4Performance IQ = 124; Verbal IQ = 111Visual = 130; Motor = 97
5Brief cyanotic spell after admissionCompleted JIFee evaluation. Comment by psychologist: “Did visual-motor tasks carefully, slowly. Moderately talkative. Not antsy.”Normal by child neurologistNo concerns, age 5Normal4Performance IQ = 105; Verbal IQ = 93Visual = 130; Motor = 124
6NoneFamily has moved to Europe. At a well child visit at 3 years 10 months, neurologic examination and developmental milestones were normal and the child was noted to be “very articulate.”Normal by primary pediatrician at 3.8 yearsNot doneNot doneNot doneNot doneNot done
7NoneJIFee evaluation pending. Multiple episodes of otitis media, intermittent conductive but no sensorineural hearing loss.Normal by primary pediatrician age 3.5 yearsNo concerns, age 4Not doneNot doneNot doneNot done
8NoneStill trying to reach for JIFee. Regular well baby visits through 18 months, all normal. At 18 months, “healthy, thriving,” normal development, 10+ words.Normal by primary pediatrician at 18 monthsNot doneNot doneNot doneNot doneNot done
9NoneEnrolled in JIFee, full evaluation pending.Normal by primary pediatrician at 6 monthsNo concerns, age 4Not doneNot doneNot doneNot done
10NoneFamily moved out of state, but finally reached by telephone by T.B.N. at age 3.7 years, hence PEDS not blinded.Normal by primary pediatrician at 15 daysSpeech therapy since age 3.3; no other concerns, age 3.7Not doneNot doneNot doneNot done
11NoneEnrolled in JIFee; full evaluation pending.Normal by primary pediatrician at 22 monthsNo concerns except “pigeon toed” and “has temper,” age 3Not doneNot doneNot doneNot done
  • CBC-L indicates Child Behavior Checklist; VMI, visual-motor integration; MPC, Motor Performance Checklist; IQ, intelligence quotient; SIDS, Sudden infant death syndrome.

  • Scored 1 point for each item failed. To date in the JIFee control group (N = 84); 32% have scores ≥4.