TABLE 4.

Prevalence and Adjusted OR* for the Relationship Between the ACE Score and Age at Initiation of Illicit Drug Use and Lifetime Use

ACE ScoreAge at Initiation of Drug Use
N≤14 Years15–18 YearsAdult (≥19 Years)Lifetime
%OR%OR%OR%OR
028120.71.0 (Referent)3.81.0 (Referent)4.81.0 (Referent)9.41.0 (Referent)
122051.51.5 (0.9–2.7)6.51.4 (1.1–1.8)7.21.4 (1.1–1.8)15.21.5 (1.2–1.8)
213383.12.9 (1.6–5.0)9.31.8 (1.3–2.4)9.81.9 (1.5–2.4)22.32.3 (1.9–2.8)
38494.74.0 (2.3–7.1)10.61.9 (1.4–2.6)10.31.9 (1.4–2.6)25.62.5 (2.0–3.2)
45074.13.8 (2.0–7.2)13.42.7 (1.9–3.8)11.22.1 (1.5–3.0)28.83.1 (2.4–4.0)
≥59029.99.1 (5.4–15.2)14.32.5 (1.9–3.3)13.22.5 (1.9–3.2)37.44.3 (3.5–5.4)
Total86132.87.78.018.5
  • * ORs adjusted for gender, baseline age, race, and educational attainment.

  • The trend for increasing ORs as the ACE score increases is significant (P < .05) in each model.