TABLE 3.

Immunogenicity of 2 Doses of T-CAIV (107 TCID50)

Vaccine StrainPrevaccine* SerostatusFourfold HAI Increase n/N (%)HAI Titer ≥1:32 n/N (%)
A/Shenzhen/95(H1N1)Seronegative389/476 (82)231/476 (49)
All children389/500 (78)256/501 (51)
A/Texas/91(H1N1)Seronegative78/153 (51)34/153 (22)
All children90/209 (43)8/209 (41)
A/Wuhan/95(H3N2)Seronegative388/391 (99)361/391 (92)
All children438/709 (62)668/710 (94)
B/Harbin/94Seronegative464/469 (99)349/469 (74)
All children520/709 (73)555/710 (78)
  • Data integrated for serum HAI responses in 3 studies.

  • * Seronegative indicates ≤1:4 HAI titer.

  • The A/Texas/36/91(H1N1) strain was used in 2 studies and A/Shenzhen/227/95 was used in 2 studies.