TABLE 2.

Reactogenicity Rates in Studies of T-CAIV (107 TCID50) in Healthy Children 1 to 8 Years of Age

Events*After Dose 1After Dose 2
T-CAIV (%)Placebo (%)T-CAIV (%)Placebo (%)
Cough26.928.727.429.0
Runny nose/nasal discharge57.648.042.942.2
Congestion10.08.66.67.4
Sore throat9.57.16.16.4
Headache4.24.13.62.3
Chills6.84.46.04.4
Vomiting16.113.112.511.8
Decreased activity
Fever
 Grade 116.412.311.310.1
 Grade 22.93.52.33.5
 Grade 3§0.00.10.30.5
  • * Days 0 to 10 after immunization.

  • Oral temperature >100°F, rectal or aural temperature >100.6°F, or axillary temperature >99.6°F.

  • Oral temperature >102°F, rectal or aural temperature >102.6°F, or axillary temperature >101.6°F.

  • § Oral temperature >104°F, rectal or aural temperature >104.6°F, or axillary temperature >103.6°F.