TABLE 1.

Screening Results in 11 Patients With Variable Positivity to EMA Assay at Diabetes Onset and During Follow-up, With Findings in Jejunal Biopsy

PatientsOnsetFollow-up (Years)
123456Biopsy
1NegNegNegPos+Pos+*NegNegMarsh 1
2Pos+NegNI
3Pos+NegNegNegNegNegNI
4NegNegNegNegPos+NegNegNI
5Pos+NegPos+*NegNegNegMarsh 1
6NegPos+NegNegNegNI
7Pos+NegNegNI
8NegPos+Pos+NegNegNegNegRefused
9Pos+NegNegPos+Refused
10NegNegPos++*Pos+*Marsh 1
11Pos+*NegNegNegNegNormal
  • Neg indicates negative assay; Pos, positive assay; + and ++, grading of positivity to EMA assay; NI, not indicated.

  • * Time when jejunal biopsy was performed.

  • HLA typing available.

  • DR3-DQ2 haplotype.