TABLE 2

Screening for Risk Factors: Acquired or Inherited Thrombotic Disorder in Pediatric Patients With Ischemic Stroke

Plasma/Protein BasedDNA Based
Activated protein C resistanceFactor V G1691A
Protein C activity/antigenProthrombin G20210A
Free and total protein S antigen
Antithrombin activity/antigen
Lipoprotein (a)
Fasting homocysteine
Lupus anticoagulant/antiphospholipid antibodies
Fibrinogen (Clauss)
Plasminogen
Factor VIIIC
  • Some experts make these recommendations for screening in pediatric stroke cases38; however, no such recommendations exist for IPS cases, and their cost versus benefits are not known.