Other Neonatal Outcomes
| Intervention Centers | Control Centers | Adjusted P | |||||
|---|---|---|---|---|---|---|---|
| % | OR (95% CI), Year 3 vs Year 1 | % | OR (95% CI), Year 3 vs Year 1 | ||||
| Year 1 | Year 3 | Year 1 | Year 3 | ||||
| Severe intraventricular hemorrhage | 14.4 | 18.1 | 13.3 | 14.1 | 0.28 (.03)a | ||
| PMA of <26 wk | 26.2 | 45.6 | 2.33 (1.38–3.94) | 26.0 | 28.6 | 1.12 (0.72–1.75) | .04 |
| PMA of ≥26 wk | 10.8 | 8.8 | 0.83 (0.53–1.31) | 8.4 | 8.7 | 1.05 (0.68–1.60) | .47 |
| Periventricular leukomalacia | 1.5 | 1.9 | 1.23 (0.50–3.00) | 2.2 | 1.5 | 0.68 (0.32–1.47) | .33 |
| Retinopathy of prematurity, stage ≥3 | 13.3 | 16.4 | 1.49 (1.01–2.26) | 16.3 | 17.0 | 1.10 (0.79–1.54) | .26 |
| Necrotizing enterocolitis, stage ≥2 | 7.8 | 8.9 | 1.10 (0.73–1.66) | 9.1 | 10.3 | 1.19 (0.85–1.66) | .77 |
| One or more of above morbidities | 84.6 | 84.3 | 0.96 (0.68–1.35) | 84.8 | 83.7 | 0.97 (0.72–1.32) | .95 |
| Discharged with oxygen | 19.6 | 12.6 | 8.4 | 9.2 | .34 (.02)a | ||
| Gestational age of <26 wk | 25.8 | 28.6 | 0.88 (0.32–2.42) | 24.8 | 30.2 | 1.28 (0.65–2.52) | .55 |
| Gestational age of ≥26 wk | 15.6 | 10.6 | 0.68 (0.43–1.08) | 5.1 | 5.1 | 0.94 (0.52–1.68) | .41 |
For dichotomous variables, the model compared the differences in the ORs for year 3 versus year 1 for the intervention and control groups. See “Methods“ for elements included in the model.
↵a Variable shows significant effect modification by gestational age (P = .03); overall results and results according to gestational age group are shown. The significance of interaction term is shown in parentheses.