TABLE 3

Respiratory Outcomes for Intervention and Control Groups

VariablesBenchmark Centers, Year 1Intervention CentersControl CentersP
Year 1Year 3Change Score/ OR (95% CI), Year 3 vs Year 1aYear 1Year 3Change Score/ OR (95% CI), Year 3 vs Year 1a
Continuous
    Total duration of ventilation, mean ± SD, d13.8 ± 19.715.0 ± 18.214.3 ± 19.3−1.2 (−3.1 to 0.7)16.1 ± 21.314.9 ± 19.5−0.9 (−2.5 to 0.7).79
    Duration of ventilation in first 7 d, mean ± SD, d3.5 ± 2.84.0 ± 2.73.5 ± 2.8−0.6 (−0.8 to −0.3)3.5 ± 2.83.4 ± 2.8−0.0 (−0.3 to 0.2).0026
    Duration of CPAP, mean ± SD, d6.6 ± 9.58.5 ± 11.98.0 ± 11.49.4 ± 11.29.3 ± 11.5.21
    Duration of oxygen therapy, mean ± SD, d28.1 ± 26.733.2 ± 27.029.0 ± 27.0−4.9 (−7.6 to −2.2)34.3 ± 27.931.7 ± 27.7−2.2 (−4.5 to 0.1).14
Dichotomous
    CPAP use on day 1 of life, %15.816.924.21.71 (1.27–2.30)26.528.21.09 (0.85–1.39).08
    Surfactant use, %66.675.876.90.96 (0.71–1.30)73.574.91.16 (0.90–1.49).35
    Pneumothorax, %6.78.17.40.85 (0.55–1.31)5.76.11.10 (0.72–1.68).40
  • See “Methods” for elements included in the model

  • a For continuous variables, the model compared the differences in the change scores between year 1 and year 3 for intervention and control groups; for dichotomous variables, the model compared the differences in the ORs.