TABLE 4

Hospital Course and Clinical Complications of Children Hospitalized With CA LCI: Philadelphia, 2000–2004

ComplicationHigh-Risk ConditionsaP
All (N = 745), n (%)Present (N = 363), n (%)Absent (N = 382), n (%)OR (95% CI)b
LOS >6 d90 (12)59 (16)31 (8)2.2 (1.4–3.5)<.001
Admission to ICUc138 (19)82 (23)56 (15)1.7 (1.2–2.5).006
Any influenza-related complication186 (25)107 (29)79 (21)1.6 (1.1–2.2).006
    Deathd5 (1)3 (1)2 (1)1.6 (0.3–9.5).7
    Suspected bacterial pneumonia110 (15)66 (18)44 (12)1.7 (1.1–2.6).01
    Seizure55 (7)31 (9)23 (6)1.5 (0.8–2.6).2
    Respiratory failure32 (4)23 (6)9 (2)2.8 (1.3–6.1).01
    Myositis16 (2)7 (2)9 (2)0.8 (0.3–2.2).8
    Encephalopathy7 (1)3 (1)4 (1)0.8 (0.2–3.5).99
    Bacteremia4 (1)2 (1)2 (1)1.0 (0.1–7.5).99
    Cardiomyopathy0 (0)NANANANA
  • NA indicates not applicable.

  • a Presence of any chronic medical condition is recognized by the ACIP as increasing the risk of influenza-related complications.

  • b The odds of a complication in the presence of a high-risk condition.

  • c Admission or transfer to PICU, CICU, or NICU.

  • d Thirty-day in-hospital mortality.