TABLE 2

Associations Between Factors at Time 1 and New-Onset Fatigue, Persistent Fatigue, and New-Onset CF at Time 2

Factors Assessed at Time 1New Cases of Fatigue at Time 2 (n/N = 166/548)Participants With Fatigue at Time 1: Prognosis of Fatigue at Time 2 (n/N = 151/283)New Cases of Chronic, Severe Fatigue With Disability at Time 2a (n/N = 9/839)
Univariate OR (95% CI)Multivariate OR (95% CI)Univariate OR (95% CI)Multivariate OR (95% CI)Univariate OR (95% CI)Multivariate OR (95% CI)
Age1.30 (1.14–1.49)b1.34 (1.16–1.54)b1.33 (1.11–1.58)c1.45 (1.19–1.77)b1.35 (0.82–2.22)1.15 (0.61–2.20)
Female gender1.43 (0.99–2.07)1.77 (1.20–2.61)c1.82 (1.13–2.93)d2.12 (1.25–3.60)d0.82 (0.22–3.07)1.00 (0.24–4.18)
Social class (I, II, III versus IIIM, IV, V)1.04 (0.72–1.51)0.74 (0.46–1.21)0.46 (0.09–2.29)
Ethnicity (white versus nonwhite)1.16 (0.57–2.38)1.98 (0.73–5.36)1.66 (0.21–13.53)
IQ1.00 (0.99–1.01)1.02 (1.01–1.04)c1.03 (1.01–1.05)b0.99 (0.95–1.03)
Any anxiety or depressive disorder4.88 (1.80–13.2)c4.33 (1.49–12.6)d1.99 (0.73–5.36)30.2 (7.75–117)b22.45 (4.86–103)b
Any conduct disorder3.16 (1.36–7.36)d3.01 (1.18–7.68)d2.40 (0.63–9.26)7.13 (1.42–35.7)d1.34 (0.19–9.37)
Hyperkinetic disorder0.57 (0.06–5.16)ee
Tired at time 11.57 (0.42–5.90)
Mother's GHQ score1.05 (1.00–1.12)1.09 (1.00–1.17)d1.11 (1.02–1.21)d1.18 (1.01–1.38)d1.08 (0.91–1.29)
Mother educated “A” level or above1.05 (0.71–1.55)1.80 (1.11–2.92)d1.31 (0.75–2.28)2.40 (0.64–9.00)
Mother: single (versus partner)1.53 (0.97–2.41)1.82 (0.96–3.46)3.78 (1.00–14.3)
  • a Severe fatigue of at least 6 months' duration with nonrestorative rest and functional impairment.

  • b P < .0005

  • c P < .005.

  • d P < .05.

  • e Not possible to analyze because cell sizes were too small.