TABLE 2

Causes of Menstrual Irregularity

Pregnancy
Endocrine causes
    Poorly controlled diabetes mellitus
    Polycystic ovary syndrome (PCOS)
    Cushing disease
    Thyroid dysfunction
    Premature ovarian failure
    Late-onset congenital adrenal hyperplasia
Acquired conditions
    Stress-related hypothalamic dysfunction
    Medications
    Exercise-induced amenorrhea
    Eating disorders (both anorexia and bulimia)
Tumors
    Ovarian tumors
    Adrenal tumors
    Prolactinomas