Table 5.

Follow-Up of Preterm Infants Who Did Not Initially Improve on Cisapride Treatment

RI BaselineRI After CisaprideRI
Follow-Up 1
RI
Follow-Up 2
Dose Initial (Final)Comments
 4 9.210.3 1.80.09 (0.2)Increased dose improved RI.
14 6.6
QTc = 0.417 s
9.7
QTc = 0.470 s
0.1 (0)Prolonged QTc interval, cisapride discontinued.
3 7.210.20.1No follow-up.
19 5.918.821.436.20.09 (0.2)Increased dose did not improve RI (follow-up 1). Cisapride discontinued. Reglan started. Follow-up 2 showed no improvement on Reglan.
2423.223.7 2.50.1 (0.2)Increased dose improved RI. Discharged on cisapride.
21 6.032.60.1No follow-up.
1710.2
QTc = 0.395 s
12.9
QTc = 0.470 s
6.518.40.09 (0.25)Increased dose improved RI (follow-up 1). Prolonged QTc interval, cisapride discontinued. Reglan started. Follow-up 2 showed no improvement on Reglan.
1115.8
QTc = 0.410 s
18.4
QTc = 0.473 s
12.10.1 (0)Prolonged QTc interval, cisapride discontinued. Started on Reglan.
  • Dose indicates cisapride dose (mg/kg/dose 4 times daily).