Univariate Analysis of Perinatal and Neonatal Characteristics Among Low-, Middle-, and High-Mortality Hospitals

Perinatal and Neonatal FactorsLow-Mortality HospitalsMiddle-Mortality HospitalsHigh Mortality HospitalsP
Mortality rate4.811.017.1<.01
Gestational age, wk29.1 ± 3.228.9 ± 3.428.8 ± 3.4.19a
Birth weight, g1041 ± 2941031 ± 2951000 ± 315.03
Male gender54.752.251.9.50a
5-min Apgar score7.37 ± 1.747.41 ± 2.167.16 ± 2.35.05
Major congenital anomalies, %
Maternal hypertension, %16.416.411.6.01
Maternal DM/GDM, %<.01
PROM, %23.433.126.4<.01
Chorioamnionitis, %14.618.811.8<.01
Histologic chorioamnionitis, %<.01
Cesarean section, %75.468.967.3<.01
Resuscitation with endotracheal intubation, %52.751.439.6<.01
Respiratory distress syndrome, %50.557.945.4<.01
HFO, %31.026.720.4<.01
Postnatal steroid for CLD, %10.515.06.9<.01
PDA, %27.723.521.7.03
Gastrointestinal perforation, %<.01
Postnatal steroid for AOP, %<.01
Number of infants admitted65.2 ± 21.174.9 ± 36.167.9 ± 21.3<.01
  • HFO indicates high-frequency oscillatory ventilation. Factors that neither differed significantly nor changed constantly among the groups included multiple birth, light for GA, 1-minute Apgar score, antenatal steroid usage, intrauterine infection, pulmonary surfactant usage, air leak syndrome, pulmonary hemorrhage, oxygen at 36 weeks, IVH, sepsis, and collected age at discharge among survivors. Variables that differed significantly among groups were further analyzed using multivariate analysis.

  • a These factors were also selected as independent variables for a logistic-regression model because they were decreased constantly across the groups, although the differences were not significant.