TABLE 1

Characteristics of the SCALE Population

CharacteristicAll Subjects (N = 742)Nonfatty Liver (N = 532)Fatty Liver (N = 97)Steatohepatitis (N = 22)
Age, mean (SE), ya14 (0.2)12.9 (0.3)17.2 (0.3)17.7 (0.5)
Gender, n (%)b
    Male531 (72)364 (68)78 (80)18 (82)
    Female211 (28)168 (32)19 (20)4 (18)
Race/ethnicity, n (%)c
    Asian67 (9)51 (10)6 (6)3 (14)
    Black, non-Hispanic81 (11)69 (13)4 (4)2 (9)
    Hispanic250 (34)161 (30)45 (46)5 (23)
    White, non-Hispanic328 (44)243 (46)37 (38)9 (41)
    Other16 (2)8 (2)5 (5)3 (14)
BMI, kg/m2a
    Mean (SE)23.2 (0.2)21.4 (0.2)30.2 (0.6)33.6 (1.6)
    Percentile, mean (SE)69.9 (1.0)65.6 (1.3)89.5 (1.7)90.9 (4.2)
  • The liver histology for all subjects was subclassified as: 0% steatosis (nonfatty); >0% and <5% steatosis (indeterminate); or ≥5% steatosis (fatty liver). Data are shown only for those with a nonfatty or fatty liver. In addition, those subjects with fatty liver were further subclassified as to whether they had steatohepatitis. Thus, the 22 subjects shown with steatohepatitis are a subset of the 97 subjects with fatty liver.

  • For fatty liver versus nonfatty liver:

  • a P < .0001;

  • b P < .02;

  • c P < .001.