Table 2.

Values of Selected Immunologic Characteristics of HIV-Infected and -Uninfected Children*

ParameterGroup 1Group 2Group 3PValue
n = 122n = 37n = 12
CD4+percent19 (± 9)38 (± 11)40 (± 6)<.0001
CD4+count1323 (± 907)2369 (± 1862)2105 (± 705)<.0001§
CD8+percent46 (± 11)28 (± 10)29 (± 13)<.0001
CD4+/CD8+ratio.44 (± .29)1.57 (± .78)1.65 (± .72)<.0001§
WBC count12 827 (± 5193)11 392 (± 4615)10 775 (± 6066).27
Lymphocyte percent56 (± 11)54 (± 13)54 (± 14).61
T-lymphocyte percent65 (± 10)64 (± 9)66 (± 10).79
  • WBC indicates white blood cell.

  • * Values are means (± standard deviation) per cubic millimeter of blood. Approximately 80% of the children were tested after 1 year of age; the rest were tested at enrollment at a median age of 8 months.

  • Group 1 were HIV-infected children; group 2, HIV-uninfected children born to HIV-seropositive mothers; group 3, children born to HIV-seronegative mothers.

  • One-way analysis of variance test.

  • § Based on log10-transformed data.